Indication: Chronic wounds and surgical wounds
Regulatory Category: Topical Pharmaceutical
Chemistry: Small molecules optimized for topical application
Development stage: Preclinical
Lead candidate: ZN-2911
Pharmacodynamic profile: Confidential
Pharmacokinetic profile: Ideal compound solubility and distribution in the wound. Good penetration through relevant layers of the skin.
Indication: Dermatology (skin aging / senescence)
Regulatory Category: Topical dermocosmetic
Chemistry: Novel small molecules optimized for topical administration
Development stage: Preclinical
Lead candidate: Senectin D
Pharmacodynamic profile: Confidential
Pharmacokinetic profile: Optimized for topical administration with good penetration into deeper layers of the skin.
Indication: Osteoarthritis
Regulatory Category: Systemic Pharmaceutical
Chemistry: Novel small molecules optimized for systemic administration
Development stage: Preclinical
Lead candidates: ZN-4262, ZN-4265, ZN-4269
Pharmacodynamic profile: Confidential
Pharmacokinetic profile: Optimized for oral administration. Good distribution to relevant peripheral tissues.
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